I have non-pitting swelling around the surrounding area of the ankles.?

I am 34 years old, and for the past 4 months, I have been experiencing swelling in the surrounding area near the ankles of both feet. I also have tingling and numbness in my feet. Along with those things, a lot of the time, I have a difficult time taking a deep breath. I have had a stress test, echo, EKG--all negative. Cholesterol, triglycerides--both great. A little bit of history though... I only have one kidney that functions. Could this be related to this or could it be related to hormonal imbalances? It seems to get worse prior to my menstrual cycle and during. Also, the muscles in my chest are very tender to touch. I would greatly appreciate any suggestions that any one has. I have been to numerous doctors--no one seems to be able to pinpoint what is going on. One says GERD and put me on protonix, another says anxiety and put me on xanax, and my PCP put me Metoprolol hoping this would help.